Anemia is frequently seen in advanced disease.

贫血在进展期中最常见.

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At this point these are all reasonable choices for patients with advanced disease.

从这一点上看,对晚期患者,这些方案均为合理选择.

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KIT expression was associated with advanced disease and with decreased incidence of bone metastases.

KIT的表达情况与疾病晚期和减少骨转移的发病率有关.

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But once these symptoms begin to develop, it may be a sign of more advanced disease.

一旦这些症状出现, 可能就是疾病进展的征兆.

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