Conclusion STI 571 could induce leukemia cells of ANLL into terminal differentiation by inhibiting c - kit tyrosine kinase.

结论STI571对急性非淋巴细胞白血病原代细胞有诱导向同系终末分化的作用,对c-kit酪氨酸激酶有明显的抑制作用,且与药物浓度相关.

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Objective : To investigate the expression of GATA - 2 gene in ANL L, CML and MDS.

目的: 了解GATA - 2基因在急性非淋巴细胞白血病(ANLL ) 、 慢性粒细胞白血病(CML) 和骨髓增生异常综合征(MDS)中的表达情况.

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