Ras gene mutation in childhood AML was mainly found in M 2 , M 4 , M 5 subtypes.

AML患儿中ras基因突变多见于M2 、 M4及M5型.

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Cells with Ras gene mutation or transformed by Ras become resistant to p 53 dependent apoptosis.

Ras基因转染或突变的细胞能够对DNA损伤 引起的p53依赖性凋亡产生抗性.

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Continuing activation of ras gene will lead to cell proliferation and cause immortal cells.

ras基因的持续的激活可导致细胞的增殖和永生化.

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Conclusbo : It'suggsts that ras gene aed p 53 gene mutation may be related with L - form infedtbo.

结合提示L型感染参与了ras原癌基因激活和p53抑癌基因的失活.

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