BMS 182874 significantly inhibited the proliferative response of VSMC evoked by oxLDL.

ETRA拮抗剂BMS-182874明显抑制oxLDL引起的增殖作用.

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MAPK inhibitor ( PD 98059 ) inhibited the phosphorylation of GSK - 3 P and almost completely blocked oxLDL - induced tubular EMT.

MAPK抑制剂 PD98059 可抑制GSK -3 β的磷酸活化,并几乎完全阻断oxLDL诱导的肾小管上皮细胞转分化,但对LDL诱导 的小管上皮细胞转分化只有部分阻断作用.

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