Result Nicardipine can induce rat mesangial cell apoptosis in vivo.

结论尼卡地平在体内有诱导大鼠系膜细胞凋亡的作用.

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Mesangial cell nuclei showed irregular shape and mitochondria swelled, stroma was normal.

系膜细胞核不规则,胞质内线粒体肿胀.系膜基质正常.

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PGF _ 2α, U 46619 LTC _ 4 , LTD _ 4 also increased mesangial cell Diacylglycerol ( DAG ) mass levels.

PGF2α 、 U46619、LTC4、LTD4促进系膜细胞合成二脂酰甘油 ( diacylglycerol,DAG ).

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Objective To study the effect of nicardipine on rat mesangial cell apoptosis in vivo.

目的探讨尼卡地平体内对大鼠系膜细胞凋亡的诱导作用.

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