Amphoteric monomer is prepared with acrylic acid , dimethylamine and chloroethanol by Mannich reaction.

以丙烯酸、二甲胺、环氧氯丙烷为原料,通过曼尼希反应制得两性离子单体.

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The other two activated hydrogens still can take place mannich reaction with amine and formaldehyde.

余下的两个活性氢位置仍然能与胺类、醛类发生曼尼期碱的缩合反应.

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Method Topotecan hydrochloride was synthesized from camptothecin by improved hydrogenation oxidation and the Mannich reaction.

方法以天然产物喜树碱为原料,经氢化还原、化制得中间体10羟基喜树碱,再与双(甲氨基)烷反应制备盐酸拓扑替康.

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